Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297131 | 0.89 | MCHR1 (0.54) | MCHR1ITGB3ITGA2BDPP4NAMPT | |
| SCHEMBL7297755 | 0.87 | ITGB3 (0.59) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7308603 | 0.86 | ITGB3 (0.66) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7295945 | 0.84 | MCHR1 (0.45) | MCHR1ITGB3ITGA2BDRD2 | |
| SCHEMBL7306495 | 0.83 | MCHR1 (0.61) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7309480 | 0.82 | ITGB3 (0.66) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7300538 | 0.80 | ITGB3 (0.75) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7300982 | 0.79 | KDM4E (0.55) | ITGB3ITGA2BNAMPTDRD2 | |
| SCHEMBL7312245 | 0.78 | ITGB3 (0.42) | MCHR1ITGB3ITGA2BNAMPT | |
| SCHEMBL7306419 | 0.78 | CYP4F2 (0.45) | MCHR1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |