Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250300 | 0.80 | GAA (0.44) | NPC1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL1402452 | 0.79 | MEN1 (0.45) | NPC1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL5250296 | 0.79 | MEN1 (0.43) | NPC1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL7298703 | 0.75 | MAPT (0.45) | NPC1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL30307078 | 0.74 | CYP1A2 (0.60) | NPC1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL5746518 | 0.74 | CYP1A2 (0.60) | NPC1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL29171124 | 0.74 | ALDH1A1 (0.47) | NPC1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL1402602 | 0.72 | CYP1A2 (0.52) | SMN1; SMN2MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL809259 | 0.71 | ADRA2A (0.38) | NPC1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL443530 | 0.71 | CA12 (0.55) | NPC1SMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |