Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | MASP2 | O00187 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 5/20 | 0.34 |
| ▸ | CTSK | P43235 | 5/20 | 0.34 |
| ▸ | CAPN2 | P17655 | 6/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 4/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313815 | 1.00 | ITGB3 (0.45) | ITGB3ITGA2BMASP2CTSSCTSK | |
| SCHEMBL7275398 | 0.93 | ITGB3 (0.40) | ITGB3ITGA2BMASP2CTSSCTSK | |
| SCHEMBL7314181 | 0.91 | ITGB3 (0.49) | ITGB3ITGA2BKDM4EMEN1MLNR | |
| SCHEMBL7301568 | 0.91 | ITGB3 (0.47) | ITGB3ITGA2BMASP2CTSSCTSK | |
| SCHEMBL7313594 | 0.91 | ITGB3 (0.49) | ITGB3ITGA2BMASP2CTSSCTSK | |
| SCHEMBL7314657 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BMASP2CTSSCTSK | |
| SCHEMBL7309683 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BMASP2CTSSCTSK | |
| SCHEMBL7315002 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BMASP2CTSSCTSK | |
| SCHEMBL7313682 | 0.89 | ITGB3 (0.36) | ITGB3ITGA2BMASP2CTSSCTSK | |
| SCHEMBL7310281 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BMASP2CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567966-B1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 1998-09-02 | — | — | EP | claimed |
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | claimed |
| EP-0567966-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | claimed |
| EP-0567966-B1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 1998-09-02 | — | — | EP | disclosed |
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | disclosed |
| EP-0567966-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |