Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313815 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BKDM4EMEN1MLNR | |
| SCHEMBL7306502 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BKDM4EMEN1MLNR | |
| SCHEMBL7310784 | 0.91 | ITGB3 (0.54) | ITGB3ITGA2BHRH3LTA4H | |
| SCHEMBL7310413 | 0.91 | ITGB3 (0.54) | ITGB3ITGA2BHRH3LTA4H | |
| SCHEMBL7314678 | 0.91 | ITGB3 (0.54) | ITGB3ITGA2BHRH3LTA4H | |
| SCHEMBL7312515 | 0.90 | ITGB3 (0.62) | ITGB3ITGA2BKDM4EMEN1MLNR | |
| SCHEMBL7308669 | 0.90 | ITGB3 (0.55) | ITGB3ITGA2BHRH3LTA4H | |
| Hydrochloric Acid SCHEMBL7314036 | 0.89 | ITGB3 (0.61) | ITGB3ITGA2BKDM4EMEN1MLNR | |
| SCHEMBL7312948 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BHRH3KDM4EKMT2A | |
| SCHEMBL7284983 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BHRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567966-B1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 1998-09-02 | — | — | EP | disclosed |
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | disclosed |
| EP-0567966-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |