SCHEMBL8408384

SCHEMBL8408384

[O]c1ccc(O)c2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 7/20 0.68
EP300 Q09472 3/20 0.52
KAT2B Q92831 3/20 0.52
KAT8 Q9H7Z6 3/20 0.52
HDAC3 O15379 1/20 0.52
NCOR2 Q9Y618 1/20 0.52
LDHA P00338 1/20 0.50
CTSB P07858 1/20 0.48
CYP1A2 P05177 1/20 0.44
APP P05067 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
CASP1 P29466 1/20 0.44
SNCA P37840 1/20 0.44
RECQL P46063 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29638 0.83 IDO1 (1.00) IDO1EP300KAT2BKAT8HDAC3
Naphthoquinone SCHEMBL10865359 0.83 ALDH1A1 (0.39) IDO1CYP1A2MAPTHPGDTSHR
SCHEMBL32677325 0.83 IDO1 (1.00) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL29362983 0.83 IDO1 (1.00) IDO1EP300KAT2BKAT8HDAC3
Catechol SCHEMBL9720436 0.77 IDO1 (0.87) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL9721905 0.77 IDO1 (0.87) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL442916 0.75 IDO1 (0.81) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL13265824 0.75 IDO1 (0.81) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL7298157 0.73 PTPN22 (0.46) IDO1CYP1A2APPMAPTTHRB
SCHEMBL7299430 0.73 HPGD (0.70) IDO1EP300KAT2BKAT8HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850635-B1 Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set OREAL (FR) 1999-07-14 EP claimed
EP-0850635-A1 Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set L'OREAL (FR) 1998-07-01 EP claimed
EP-0850635-B1 Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set OREAL (FR) 1999-07-14 EP disclosed
EP-0850635-A1 Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set L'OREAL (FR) 1998-07-01 EP disclosed
US-4202816-A ENOL-PIPERIDINE METAL COMPLEXES CIBA-GEIGY CORPORATION (US) 1980-05-13 US disclosed