Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318422 | 0.87 | BACE1 (0.46) | NPC1RAB9ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL11013555 | 0.87 | BACE1 (0.46) | NPC1RAB9ASMN1; SMN2BACE1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7306561 | 0.86 | BACE1 (0.45) | NPC1RAB9ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL7309626 | 0.85 | SIRT5 (0.43) | BACE1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL7317736 | 0.84 | MAPT (0.43) | BACE1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL19030217 | 0.83 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2BACE1ALDH1A1 | |
| SCHEMBL7321233 | 0.83 | MAPT (0.42) | BACE1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL7317041 | 0.83 | MAPT (0.42) | BACE1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL10843127 | 0.82 | MAPT (0.44) | BACE1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL6529605 | 0.82 | MAPT (0.44) | NPC1RAB9ASMN1; SMN2BACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |