Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.52 |
| ▸ | F2 | P00734 | 10/20 | 0.40 |
| ▸ | F10 | P00742 | 8/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299889 | 0.94 | ITGB3 (0.52) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7307930 | 0.93 | ITGB3 (0.50) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7298548 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7306404 | 0.88 | ITGB3 (0.66) | ITGB3ITGA2BALOX5PLAU | |
| SCHEMBL7306922 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BF2ALOX5MTNR1A | |
| SCHEMBL7388902 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BMTNR1A | |
| SCHEMBL7387130 | 0.85 | ITGB3 (0.46) | ITGB3ITGA2BF10MTNR1A | |
| SCHEMBL7311321 | 0.83 | ITGB3 (0.50) | ITGB3ITGA2BF2F10PLAU | |
| SCHEMBL7309823 | 0.83 | ITGB3 (0.76) | ITGB3ITGA2BF10PLAU | |
| SCHEMBL7300485 | 0.83 | ITGB3 (0.67) | ITGB3ITGA2BF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |