Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386307 | 0.95 | ITGB3 (0.56) | ITGB3ITGA2BRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7395937 | 0.94 | ITGB3 (0.50) | ITGB3ITGA2BRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7387130 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BL3MBTL1MTNR1A | |
| SCHEMBL7388357 | 0.90 | ITGB3 (0.50) | ITGB3ITGA2BRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7395947 | 0.86 | ITGB3 (0.46) | ITGB3ITGA2BLMNAL3MBTL1MTNR1A | |
| SCHEMBL7394072 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7395667 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7388905 | 0.86 | MAPT (0.42) | ITGB3ITGA2BRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7306587 | 0.86 | ITGB3 (0.52) | ITGB3ITGA2BMTNR1A | |
| SCHEMBL7396721 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |