Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | SLC33A1 | O00400 | 2/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263270 | 0.92 | DPP4 (0.43) | PPARGDPP4SLC33A1AXLFLT3 | |
| SCHEMBL9262231 | 0.84 | PPARG (0.46) | PPARGSLC33A1AXLFLT3MERTK | |
| SCHEMBL7313123 | 0.83 | ALDH1A1 (0.46) | PPARGKDM4EHPGDLMNANPC1 | |
| SCHEMBL7312739 | 0.83 | PPARG (0.45) | PPARGAXLFLT3MERTKACHE | |
| SCHEMBL7320243 | 0.83 | PPARG (0.47) | PPARGAXLFLT3MERTKACHE | |
| SCHEMBL7319487 | 0.83 | PPARG (0.45) | PPARGAXLFLT3MERTKACHE | |
| SCHEMBL9260186 | 0.81 | PPARG (0.43) | PPARGAXLFLT3MERTKACHE | |
| Hydrochloric Acid SCHEMBL7317120 | 0.81 | SLC33A1 (0.40) | SLC33A1 | |
| SCHEMBL7316719 | 0.81 | PPARG (0.43) | PPARGAXLFLT3MERTKACHE | |
| SCHEMBL7309810 | 0.78 | ALDH1A1 (0.38) | PPARGAXLFLT3MERTKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389632-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1995-02-14 | — | — | US | disclosed |
| US-5231094-A | Cardiovascular disorders | SOCIETE ANONYME: LABORATOIRES UPSA (FR) | 1993-07-27 | — | — | US | disclosed |