Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262231 | 0.89 | PPARG (0.46) | PPARGAXLFLT3MERTKGSK3A | |
| SCHEMBL7320243 | 0.89 | PPARG (0.47) | PPARGAXLFLT3MERTKGSK3A | |
| SCHEMBL7312739 | 0.89 | PPARG (0.45) | PPARGAXLFLT3MERTKGSK3A | |
| SCHEMBL9260186 | 0.87 | PPARG (0.43) | PPARGAXLFLT3MERTKGSK3A | |
| SCHEMBL7316719 | 0.86 | PPARG (0.43) | PPARGAXLFLT3MERTKGSK3A | |
| SCHEMBL9263270 | 0.84 | DPP4 (0.43) | PPARGAXLFLT3MERTKACHE | |
| SCHEMBL7306663 | 0.83 | PPARG (0.41) | PPARGAXLFLT3MERTKACHE | |
| SCHEMBL9257925 | 0.83 | PPARG (0.41) | PPARGGSK3AGSK3BACHE | |
| SCHEMBL9263013 | 0.82 | AGTR1 (0.40) | PPARGAXLFLT3MERTKGSK3A | |
| SCHEMBL9263007 | 0.82 | PPARG (0.40) | PPARGAXLFLT3MERTKACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389632-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1995-02-14 | — | — | US | disclosed |
| US-5231094-A | Cardiovascular disorders | SOCIETE ANONYME: LABORATOIRES UPSA (FR) | 1993-07-27 | — | — | US | disclosed |