Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 7/20 | 0.65 |
| ▸ | ACE | P12821 | 3/20 | 0.61 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.59 |
| ▸ | IL1RN | P18510 | 4/20 | 0.59 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.59 |
| ▸ | MME | P08473 | 1/20 | 0.58 |
| ▸ | ANPEP | P15144 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27459375 | 1.00 | ECE1 (0.65) | ECE1ACEERAP2IL1RNERAP1 | |
| SCHEMBL7305118 | 0.90 | ECE1 (0.68) | ECE1ACEERAP2ERAP1MME | |
| SCHEMBL7313675 | 0.89 | ECE1 (0.61) | ECE1ACEERAP2IL1RNERAP1 | |
| SCHEMBL7313702 | 0.86 | ECE1 (0.61) | ECE1ACEERAP2IL1RNERAP1 | |
| SCHEMBL14503216 | 0.84 | ECE1 (0.71) | ECE1ACEERAP2ERAP1MME | |
| SCHEMBL29562240 | 0.84 | ECE1 (0.71) | ECE1ACEERAP2ERAP1MME | |
| SCHEMBL4959992 | 0.81 | ERAP2 (0.75) | ECE1ACEERAP2IL1RNERAP1 | |
| SCHEMBL4959976 | 0.81 | ERAP2 (0.75) | ECE1ACEERAP2IL1RNERAP1 | |
| SCHEMBL21411572 | 0.81 | ECE1 (0.73) | ECE1ACEERAP2 | |
| SCHEMBL21411574 | 0.81 | ECE1 (0.73) | ECE1ACEERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691985-B1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL PHARMA INC (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5608078-A | Phosphonomethyldipeptides and process for preparation thereof | MERRELL PHARMACEUTICALS INC. (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0691985-A1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022908-A1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| EP-0618224-A1 | Phosphonomethyldipeptides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-05 | — | — | EP | disclosed |