Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 8/20 | 0.61 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.59 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.59 |
| ▸ | ANPEP | P15144 | 1/20 | 0.59 |
| ▸ | IL1RN | P18510 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.57 |
| ▸ | MME | P08473 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200899 | 0.93 | ERAP1 (0.67) | ECE1ERAP2ERAP1ANPEPIL1RN | |
| SCHEMBL7313675 | 0.93 | ECE1 (0.61) | ECE1ERAP2ERAP1ANPEPIL1RN | |
| SCHEMBL7305118 | 0.88 | ECE1 (0.68) | ECE1ERAP2ERAP1ANPEPACE | |
| SCHEMBL27459375 | 0.86 | ECE1 (0.65) | ECE1ERAP2ERAP1ANPEPIL1RN | |
| SCHEMBL7306796 | 0.86 | ECE1 (0.65) | ECE1ERAP2ERAP1ANPEPIL1RN | |
| SCHEMBL7304271 | 0.85 | ERAP2 (0.51) | ECE1ERAP2ERAP1ANPEPIL1RN | |
| SCHEMBL8200511 | 0.84 | KDM4E (0.51) | ECE1ERAP2ERAP1ANPEPIL1RN | |
| SCHEMBL9289633 | 0.83 | ECE1 (0.62) | ECE1ERAP2ERAP1IL1RNACE | |
| SCHEMBL9099187 | 0.83 | ECE1 (0.60) | ECE1ERAP2ERAP1ANPEPIL1RN | |
| SCHEMBL12052806 | 0.83 | NMBR (0.71) | ECE1ERAP2ERAP1IL1RNMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691985-B1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL PHARMA INC (US) | 2000-05-03 | — | — | EP | claimed |
| US-5608078-A | Phosphonomethyldipeptides and process for preparation thereof | MERRELL PHARMACEUTICALS INC. (US) | 1997-03-04 | — | — | US | claimed |
| EP-0691985-A1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-01-17 | — | — | EP | claimed |
| WO-1994022908-A1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-13 | — | — | WO | claimed |
| EP-0618224-A1 | Phosphonomethyldipeptides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-05 | — | — | EP | claimed |
| EP-0691985-B1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL PHARMA INC (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5608078-A | Phosphonomethyldipeptides and process for preparation thereof | MERRELL PHARMACEUTICALS INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5516457-A | ULTRAVIOLET ABSORBING COMPOSITIONS | TIOXIDE SPECIALTIES LIMITED (GB) | 1996-05-14 | — | — | US | disclosed |
| US-5491173-A | ESTROGENIC, ANTIESTROGENIC AGENTS, ANTITUMOR AGENTS | ORION-YHTYMA OY (FI) | 1996-02-13 | — | — | US | disclosed |
| EP-0691985-A1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-01-17 | — | — | EP | disclosed |
| US-5443759-A | Containing metallic oxides of small particle sizes | TIOXIDE SPECIALTIES LIMITED (GB) | 1995-08-22 | — | — | US | disclosed |
| WO-1994022908-A1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| EP-0618224-A1 | Phosphonomethyldipeptides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-05 | — | — | EP | disclosed |
| US-4996225-A | Antitumor agents | FARMOS GROUP LTD. (FI) | 1991-02-26 | — | — | US | disclosed |
| US-4696949-A | ANTITUMOR AGENTS, ANTIESTROGENS | FARMOS GROUP LTD. (FI) | 1987-09-29 | — | — | US | disclosed |
| EP-0095875-B1 | NOVEL TRI-PHENYL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-09-10 | — | — | EP | disclosed |
| EP-0095875-A2 | Novel tri-phenyl alkane and alkene derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-12-07 | — | — | EP | disclosed |