Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669554 | 0.87 | CA5A (0.67) | CA5ALMNAMAPTHPGDRAB9A | |
| SCHEMBL9350174 | 0.77 | TPMT (0.55) | CA5ALMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL7307023 | 0.77 | CA5A (0.89) | CA5ALMNAHPGDKMT2AHSD17B1 | |
| SCHEMBL11762568 | 0.77 | TPMT (0.55) | CA5ALMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL2624954 | 0.77 | TPMT (0.55) | CA5ALMNAMAPTHPGDRAB9A | |
| SCHEMBL23469962 | 0.74 | CA5A (0.52) | CA5ALMNAMAPTHPGDRAB9A | |
| SCHEMBL15709749 | 0.74 | CA5A (0.52) | CA5ALMNAMAPTHPGDRAB9A | |
| SCHEMBL13307545 | 0.74 | CA5A (0.52) | CA5ALMNAMAPTHPGDRAB9A | |
| SCHEMBL22198391 | 0.74 | CA5A (0.52) | CA5ALMNAMAPTHPGDRAB9A | |
| SCHEMBL5090099 | 0.74 | CA5A (0.52) | CA5ALMNAMAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |