SCHEMBL10041772

SCHEMBL10041772

CC(=O)c1cc(C(=O)Cl)cc(C(=O)Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.52
LMNA P02545 2/20 0.43
MAPT P10636 4/20 0.37
RAB9A P51151 3/20 0.37
HPGD P15428 2/20 0.37
KMT2A Q03164 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NPC1 O15118 2/20 0.37
GSK3B P49841 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HSD17B1 P14061 1/20 0.36
CYP2A6 P11509 1/20 0.35
PKM P14618 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
NLRP1 Q9C000 1/20 0.33
TSHR P16473 1/20 0.33
PRKCI P41743 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4623865 1.00 CA5A (0.52) CA5ALMNAMAPTRAB9AHPGD
Acetone SCHEMBL28498158 0.88 LMNA (0.38) CA5ALMNAMAPTRAB9AHPGD
SCHEMBL14067800 0.87 KMT2A (0.48) CA5ALMNAMAPTKMT2AGSK3B
Ethane SCHEMBL29138437 0.85 ALDH1A1 (0.37) CA5AL3MBTL1ALDH1A1TSHR
SCHEMBL38576 0.85 ALDH1A1 (0.40) L3MBTL1ALDH1A1TSHR
SCHEMBL669554 0.85 CA5A (0.67) CA5ALMNAMAPTRAB9AHPGD
SCHEMBL14848973 0.85 HDAC8 (0.44) CA5ALMNAHPGDSMN1; SMN2ALDH1A1
Hydrochloric Acid SCHEMBL18918955 0.82 ALDH1A1 (0.39) L3MBTL1ALDH1A1TSHR
SCHEMBL13307462 0.82 ALDH1A1 (0.56) LMNAMAPTKMT2AL3MBTL1NPC1
SCHEMBL30745618 0.80 ALDH1A1 (0.50) RAB9AHPGDKMT2AL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947438-B2 Method for monitoring cement using polymer-based capsules SAUDI ARABIAN OIL COMPANY 2021-03-16 US disclosed
US-20180217498-A1 PHOTOACTIVABLE NITROGEN BASES BASF SE (DE) 2018-08-02 US disclosed
US-9921477-B2 Photoactivable nitrogen bases BASE SE (DE) 2018-03-20 US disclosed
US-9561474-B2 Composite membrane with multi-layered active layer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-02-07 US disclosed
US-20160207007-A1 CHITOSAN ULTRA-THIN FILM COMPOSITE NANOFILTRATION MEMBRANES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2016-07-21 US disclosed
US-9352286-B2 Composite filtration membranes and methods of preparation thereof GLOBALFOUNDRIES INC. (KY) 2016-05-31 US disclosed
US-9022227-B2 Composite membranes and methods of preparation thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-05-05 US disclosed
US-20140217014-A1 COMPOSITE FILTRATION MEMBRANES AND METHODS OF PREPARATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-08-07 US disclosed
US-20120241373-A1 COMPOSITE MEMBRANES AND METHODS OF PREPARATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-09-27 US disclosed
US-20120048799-A1 COMPOSITE FILTRATION MEMBRANES AND METHODS OF PREPARATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-03-01 US disclosed
US-20100105794-A1 PHOTOACTIVABLE NITROGEN BASES CIBA CORPORATION (US) 2010-04-29 US disclosed
EP-2009042-A1 Anion-binding polymers and uses thereof Ilypsa, Inc. (US) 2008-12-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180217498-A1 PHOTOACTIVABLE NITROGEN BASES CBR1, NR0B1, NR0B2 CA5A 2607/4885LMNA 1408/4885MAPT 2920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.