SCHEMBL7307308

SCHEMBL7307308

CC(C)CC(NC(=O)C(CCCCNC(=O)OCc1ccccc1)NC(=O)C(Cc1cccc2ccccc12)Cc1cccc2ccccc12)[C@@H](O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 19/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7307190 0.85 REN (0.73) REN
SCHEMBL7318357 0.84 REN (0.69) REN
SCHEMBL10725345 0.80 REN (0.61) REN
SCHEMBL10725339 0.80 REN (0.61) REN
SCHEMBL10771749 0.77 REN (0.54) REN
SCHEMBL10771745 0.77 REN (0.54) REN
SCHEMBL19586026 0.76 REN (0.62) REN
SCHEMBL19586943 0.76 REN (0.62) REN
SCHEMBL10721166 0.75 REN (0.57) REN
SCHEMBL10725413 0.75 REN (0.57) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5135914-A Controlling hypertension, hyperaldosteronism, and congestive heart failure WARNER-LAMBERT COMPANY (US) 1992-08-04 US disclosed