Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318638 | 0.88 | REN (0.75) | REN | |
| SCHEMBL7307799 | 0.88 | REN (0.75) | REN | |
| SCHEMBL7318357 | 0.86 | REN (0.69) | REN | |
| SCHEMBL7307308 | 0.85 | REN (0.59) | REN | |
| SCHEMBL7305979 | 0.76 | REN (0.52) | REN | |
| SCHEMBL7317706 | 0.76 | REN (0.52) | REN | |
| SCHEMBL7311764 | 0.75 | REN (0.64) | REN | |
| SCHEMBL10772819 | 0.75 | MMP2 (0.61) | — | |
| SCHEMBL10773268 | 0.73 | REN (0.62) | REN | |
| SCHEMBL7309704 | 0.71 | REN (0.48) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135914-A | Controlling hypertension, hyperaldosteronism, and congestive heart failure | WARNER-LAMBERT COMPANY (US) | 1992-08-04 | — | — | US | disclosed |