Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637781 | 0.94 | ITGB3 (0.42) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL7314800 | 0.92 | ITGB3 (0.50) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL7315377 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6601465 | 0.89 | ITGB3 (0.60) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6605691 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL7315747 | 0.88 | SIGMAR1 (0.50) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL7317117 | 0.87 | ITGB3 (0.55) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL7307512 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL7317069 | 0.87 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL7308804 | 0.86 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |