SCHEMBL7307413

SCHEMBL7307413

O=C(NC(Cc1ccc(Cl)cc1)C(=O)O)OCc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.67
ITGB3 P05106 8/20 0.63
ITGA2B P08514 8/20 0.63
TACR1 P25103 2/20 0.60
GPR34 Q9UPC5 1/20 0.60
CTSL P07711 1/20 0.58
CTSB P07858 1/20 0.58
CTSS P25774 1/20 0.58
CTSK P43235 1/20 0.58
ALDH1A1 P00352 1/20 0.57
ALOX15 P16050 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9825847 1.00 PPARA (0.67) PPARAITGB3ITGA2BTACR1GPR34
SCHEMBL2969722 1.00 PPARA (0.67) PPARAITGB3ITGA2BTACR1GPR34
SCHEMBL5399121 0.93 GPR34 (0.71) PPARAITGB3ITGA2BGPR34
SCHEMBL11581034 0.92 PPARA (0.58) PPARAITGB3ITGA2BTACR1GPR34
SCHEMBL11581039 0.92 PPARA (0.58) PPARAITGB3ITGA2BTACR1GPR34
SCHEMBL2855187 0.92 PPARA (0.61) PPARAITGB3ITGA2BTACR1CTSL
SCHEMBL2855186 0.92 PPARA (0.61) PPARAITGB3ITGA2BTACR1CTSL
Hypochlorous Acid SCHEMBL7368156 0.92 TACR1 (0.65) ITGB3ITGA2BTACR1CTSLCTSB
SCHEMBL220648 0.92 TACR1 (0.68) ITGB3ITGA2BTACR1CTSLCTSB
SCHEMBL219151 0.92 TACR1 (0.68) ITGB3ITGA2BTACR1CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
WO-2018184976-A1 SUBSTITUTED IMIDAZO[1,2-A]PYRIDINECARBOXAMIDES AND USE OF SAME BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-10-11 WO disclosed
EP-0643072-B1 2-Piperazinone compounds and their use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-02-24 EP disclosed
US-5550131-A ANTITHROMBOTIC AGENT TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-08-27 US disclosed
EP-0643072-A1 2-Piperazinone compounds and their use Takeda Chemical Industries, Ltd. (JP) 1995-03-15 EP disclosed