Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2432831 | 0.84 | CYP19A1 (0.51) | TDP1NQO2MTNR1AMTNR1BKDM4E | |
| SCHEMBL3004692 | 0.84 | CYP19A1 (0.51) | TDP1NQO2MTNR1AMTNR1BKDM4E | |
| SCHEMBL821438 | 0.84 | NQO2 (0.49) | NQO2MTNR1AMTNR1BKDM4ELMNA | |
| SCHEMBL16048803 | 0.84 | NQO2 (0.49) | NQO2MTNR1AMTNR1BKDM4ELMNA | |
| SCHEMBL19838576 | 0.81 | CTDSP1 (0.46) | CTDSP1TDP1KDM4ELMNAPOLB | |
| SCHEMBL19838579 | 0.81 | CTDSP1 (0.46) | CTDSP1TDP1KDM4ELMNAPOLB | |
| SCHEMBL29960412 | 0.81 | CTDSP1 (0.46) | CTDSP1TDP1KDM4ELMNAPOLB | |
| SCHEMBL7307161 | 0.80 | KMT2A (0.42) | TDP1KDM4ELMNAPOLBNPC1 | |
| SCHEMBL9290663 | 0.77 | NQO2 (0.53) | NQO2MTNR1AMTNR1BKDM4EPOLB | |
| SCHEMBL8514302 | 0.77 | NQO2 (0.53) | NQO2MTNR1AMTNR1BKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |