Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307463 | 0.80 | CTDSP1 (0.40) | KMT2APKMMEN1NPC1HPGD | |
| SCHEMBL19838576 | 0.78 | CTDSP1 (0.46) | HPGDALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL19838579 | 0.78 | CTDSP1 (0.46) | HPGDALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL29960412 | 0.78 | CTDSP1 (0.46) | HPGDALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL7307146 | 0.74 | KMT2A (0.41) | KMT2APKMMEN1NPC1HSP90AA1 | |
| SCHEMBL7307152 | 0.74 | KMT2A (0.41) | KMT2APKMMEN1NPC1HSP90AA1 | |
| SCHEMBL7917078 | 0.70 | CTDSP1 (0.44) | NPC1HPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14508734 | 0.67 | KMT2A (0.53) | KMT2APKMMEN1NPC1HSP90AA1 | |
| SCHEMBL11114081 | 0.67 | GSK3B (0.42) | KMT2APKMMEN1NPC1HSP90AA1 | |
| SCHEMBL3213966 | 0.66 | CA12 (0.51) | KMT2AMEN1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |