Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308277 | 0.86 | CA12 (0.35) | CA12CA9CCR1KCNH2POLB | |
| SCHEMBL7316730 | 0.78 | PDE3B (0.49) | MEN1KMT2ADRD2 | |
| SCHEMBL7341497 | 0.77 | PDE3B (0.43) | CA12CA9KCNH2MEN1KMT2A | |
| SCHEMBL10064553 | 0.73 | MCHR1 (0.48) | CA12CA9DRD2MCHR1 | |
| SCHEMBL7312825 | 0.72 | KDM4E (0.33) | MEN1KMT2A | |
| SCHEMBL9820774 | 0.72 | MCHR1 (0.49) | CA12CA9MEN1KMT2AMCHR1 | |
| SCHEMBL7316415 | 0.69 | MCL1 (0.36) | DRD2MCL1ALBBCL2DRD4 | |
| SCHEMBL7318084 | 0.68 | TSHR (0.46) | MEN1KMT2A | |
| SCHEMBL11864174 | 0.67 | HTR1B (0.43) | CA12CA9KMT2ADRD2 | |
| SCHEMBL11226436 | 0.67 | DRD2 (0.40) | MEN1KMT2ADRD2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |