Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.55 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430824 | 0.89 | CES2 (0.61) | CES2CES1MEN1KMT2AGPR84 | |
| SCHEMBL2440945 | 0.89 | CES2 (0.61) | CES2CES1MEN1KMT2AGPR84 | |
| SCHEMBL2442645 | 0.89 | CES2 (0.61) | CES2CES1MEN1KMT2AGPR84 | |
| SCHEMBL14976297 | 0.89 | CES2 (0.61) | CES2CES1MEN1KMT2AGPR84 | |
| SCHEMBL2444713 | 0.89 | CES2 (0.61) | CES2CES1MEN1KMT2AGPR84 | |
| SCHEMBL430826 | 0.89 | CES2 (0.61) | CES2CES1MEN1KMT2AGPR84 | |
| SCHEMBL14976704 | 0.89 | CES2 (0.61) | CES2CES1MEN1KMT2AGPR84 | |
| SCHEMBL28146618 | 0.82 | CES2 (0.39) | CES2CES1ALDH1A1TSHR | |
| SCHEMBL15710411 | 0.79 | TERT (0.61) | MEN1FAAHKMT2APPARGPPARD | |
| SCHEMBL15809511 | 0.78 | CES2 (0.59) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572952-A1 | 4-Benzylpiperidine derivatives, a process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1993-12-08 | — | — | EP | disclosed |