Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474876 | 0.78 | SCN5A (0.47) | SCN5AELANECA2NOTUMALDH1A1 | |
| SCHEMBL4061370 | 0.71 | ELANE (0.81) | ELANEKDM1ACA2L3MBTL1MAPKAPK2 | |
| SCHEMBL16154734 | 0.69 | SCN5A (0.48) | SCN5ANOTUMPOLBKDM4EALDH1A1 | |
| SCHEMBL198087 | 0.67 | ELANE (0.68) | ELANEKDM1ACA2POLBL3MBTL1 | |
| SCHEMBL2152569 | 0.67 | LMNA (0.58) | ELANEHTT | |
| SCHEMBL4059798 | 0.66 | ELANE (0.72) | ELANEKDM1ACA2MAPKAPK2 | |
| SCHEMBL4061539 | 0.65 | ELANE (0.65) | ELANEKDM1ACA2POLBL3MBTL1 | |
| SCHEMBL4057059 | 0.65 | ELANE (0.70) | ELANEKDM1ACA2KDM4E | |
| SCHEMBL217465 | 0.65 | KDM4E (0.45) | SCN5ACA2POLBL3MBTL1KDM4E | |
| SCHEMBL248547 | 0.65 | SCN5A (1.00) | SCN5ANOTUMPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854140-B1 | Vitronectin receptor antagonists, their production and their use | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-0854140-A2 | Vitronectin receptor antagonists, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-22 | — | — | EP | disclosed |