Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27872295 | 0.81 | TRPA1 (0.35) | — | |
| SCHEMBL23702732 | 0.81 | NAMPT (0.32) | GRIN2BTYRCHRNB4CHRNA3CHRNA7 | |
| SCHEMBL29790943 | 0.81 | NAMPT (0.32) | GRIN2BTYRCHRNB4CHRNA3CHRNA7 | |
| SCHEMBL18676092 | 0.80 | KDM4E (0.43) | — | |
| SCHEMBL28305452 | 0.79 | CNR1 (0.38) | HTR2CHTR2B | |
| SCHEMBL8509475 | 0.75 | PBRM1 (0.38) | — | |
| SCHEMBL7650098 | 0.71 | CA9 (0.35) | GRIN2B | |
| SCHEMBL9114452 | 0.71 | PARP10 (0.34) | — | |
| SCHEMBL2524442 | 0.71 | — | — | |
| SCHEMBL30344009 | 0.71 | KDM1A (0.37) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |