Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990613 | 0.94 | SMN1; SMN2 (0.78) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL9639138 | 0.88 | SMN1; SMN2 (0.67) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL28668503 | 0.88 | SMN1; SMN2 (0.95) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL9337868 | 0.88 | SMN1; SMN2 (0.95) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL38658755 | 0.86 | SMN1; SMN2 (0.91) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL10587847 | 0.83 | ALDH1A1 (0.83) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL7693790 | 0.82 | SMN1; SMN2 (0.77) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL6549000 | 0.82 | SMN1; SMN2 (0.84) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL27892098 | 0.82 | ALDH1A1 (0.81) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL25825789 | 0.82 | SMN1; SMN2 (0.77) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298739-A | ANTICOAGULANTS, ANTIINFLAMMATORY, ANTIULCER, VASODILATOR, PHOSPHODIESTERASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-11-03 | — | — | US | disclosed |
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |