Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671421 | 0.89 | — | — | |
| SCHEMBL7307871 | 0.88 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1HPGDEPHX1KMT2A | |
| SCHEMBL10587847 | 0.87 | ALDH1A1 (0.83) | SMN1; SMN2ALDH1A1HPGDEPHX1KMT2A | |
| SCHEMBL2990613 | 0.86 | SMN1; SMN2 (0.78) | SMN1; SMN2ALDH1A1HPGDEPHX1KMT2A | |
| SCHEMBL11804456 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HPGDEPHX1KMT2A | |
| SCHEMBL931479 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HPGDEPHX1KMT2A | |
| SCHEMBL9337868 | 0.83 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1HPGDEPHX1KMT2A | |
| SCHEMBL28668503 | 0.83 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1HPGDEPHX1KMT2A | |
| SCHEMBL227416 | 0.83 | EPHX1 (0.61) | SMN1; SMN2ALDH1A1HPGDEPHX1KMT2A | |
| SCHEMBL7440298 | 0.83 | EPHX1 (0.61) | SMN1; SMN2ALDH1A1HPGDEPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111933-A | PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | claimed |
| EP-0314450-B1 | PREPARATION OF HALO SUBSTITUTED ISOTHIAZOLONES | ROHM AND HAAS COMPANY (US) | 1992-07-29 | — | — | EP | disclosed |
| US-4861896-A | Preparation of halo substituted isothiazolones | ROHM AND HAAS COMPANY (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0314450-A1 | Preparation of halo substituted isothiazolones | ROHM AND HAAS COMPANY (US) | 1989-05-03 | — | — | EP | disclosed |
| US-4111933-A | PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |