Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.42 |
| ▸ | BCHE | P06276 | 7/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313262 | 0.98 | ACHE (0.42) | ACHEBCHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL7314468 | 0.94 | ACHE (0.43) | ACHEBCHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL7304824 | 0.92 | ACHE (0.43) | ACHEBCHEFAAHLTA4H | |
| SCHEMBL7309506 | 0.90 | ACHE (0.41) | ACHEBCHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL7304426 | 0.90 | LTA4H (0.47) | ACHEBCHEFAAHLTA4H | |
| SCHEMBL7311514 | 0.90 | ACHE (0.42) | ACHEBCHEFAAHLTA4H | |
| SCHEMBL7316449 | 0.88 | ACHE (0.43) | ACHEBCHEFAAHLTA4H | |
| SCHEMBL7312963 | 0.88 | LTA4H (0.48) | ACHEBCHEFAAHLTA4H | |
| SCHEMBL7309705 | 0.88 | LTA4H (0.47) | ACHEBCHEFAAHLTA4H | |
| SCHEMBL8661630 | 0.87 | ACHE (0.43) | ACHEBCHECACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |