Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308070 | 1.00 | GRM2 (0.50) | GRM2LMNA | |
| SCHEMBL2823472 | 0.85 | GRM2 (0.68) | GRM2LMNA | |
| SCHEMBL11233634 | 0.83 | GRM2 (0.58) | GRM2LMNA | |
| SCHEMBL7314032 | 0.83 | GRM2 (0.43) | GRM2 | |
| SCHEMBL7314041 | 0.83 | GRM2 (0.43) | GRM2 | |
| SCHEMBL5618256 | 0.82 | GRM2 (0.48) | GRM2 | |
| SCHEMBL5617534 | 0.82 | GRM2 (0.48) | GRM2 | |
| SCHEMBL5617531 | 0.82 | GRM2 (0.48) | GRM2 | |
| SCHEMBL11230811 | 0.81 | GRM2 (0.65) | GRM2 | |
| SCHEMBL27325072 | 0.78 | LMNA (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657440-B1 | Oxazolidine-2-one derivatives as MAO inhibitors | HOFFMANN LA ROCHE (CH) | 2000-04-05 | — | — | EP | disclosed |
| US-5574055-A | COGNITIVE AND NEURODEGENERATIVE DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0657440-A1 | Oxazolidine-2-one derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-14 | — | — | EP | disclosed |