Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.41 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314041 | 1.00 | GRM2 (0.43) | GRM2CTSVCTSLCTSBCTSS | |
| SCHEMBL7308062 | 0.83 | GRM2 (0.50) | GRM2 | |
| SCHEMBL7308070 | 0.83 | GRM2 (0.50) | GRM2 | |
| SCHEMBL27319009 | 0.77 | ESR2 (0.36) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL7753890 | 0.73 | ESR2 (0.47) | CTSLCTSBCTSKESR2 | |
| SCHEMBL7308961 | 0.72 | MAOA (0.51) | GRM2ESR2F10 | |
| SCHEMBL7308967 | 0.72 | MAOA (0.51) | GRM2ESR2F10 | |
| SCHEMBL5617534 | 0.72 | GRM2 (0.48) | GRM2F10 | |
| SCHEMBL5618256 | 0.72 | GRM2 (0.48) | GRM2F10 | |
| SCHEMBL5617531 | 0.72 | GRM2 (0.48) | GRM2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574055-A | COGNITIVE AND NEURODEGENERATIVE DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0657440-A1 | Oxazolidine-2-one derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-14 | — | — | EP | disclosed |