Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 16/20 | 0.64 |
| ▸ | CA2 | P00918 | 16/20 | 0.64 |
| ▸ | CA7 | P43166 | 6/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667472 | 0.83 | KMO (1.00) | KMO | |
| SCHEMBL727440 | 0.83 | KMO (1.00) | KMO | |
| SCHEMBL728320 | 0.83 | KMO (1.00) | KMO | |
| SCHEMBL7314484 | 0.79 | KMO (0.57) | KMOCA1CA2CA7CA13 | |
| SCHEMBL7319589 | 0.76 | KMO (0.72) | KMO | |
| SCHEMBL9554501 | 0.76 | KMO (0.72) | KMO | |
| SCHEMBL7312457 | 0.76 | KMO (0.71) | KMO | |
| SCHEMBL3104186 | 0.74 | TSHR (0.75) | KMO | |
| SCHEMBL7315538 | 0.74 | TSHR (0.75) | KMO | |
| SCHEMBL3104413 | 0.74 | KMO (0.68) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |