Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.57 |
| ▸ | CPA1 | P15085 | 4/20 | 0.50 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
| ▸ | CPA3 | P15088 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316863 | 0.84 | ALDH1A1 (0.58) | KMOCPA1CPB1CPA3CPB2 | |
| SCHEMBL7320178 | 0.84 | KMO (0.54) | KMOCPA1CPB1CPA3CPB2 | |
| SCHEMBL7319940 | 0.83 | AKR1C3 (0.53) | KMOCPA1CPB1CPA3CPB2 | |
| SCHEMBL7310444 | 0.81 | LTA4H (0.42) | KMOCA2CA1CA12CA9 | |
| SCHEMBL7319825 | 0.81 | MAPT (0.58) | KMOTSHR | |
| SCHEMBL7315538 | 0.80 | TSHR (0.75) | KMOCPA1CPB1CPA3CPB2 | |
| SCHEMBL3104186 | 0.80 | TSHR (0.75) | KMOCPA1CPB1CPA3CPB2 | |
| SCHEMBL7308068 | 0.79 | KMO (0.71) | KMOCA2CA1CA12CA9 | |
| SCHEMBL7312441 | 0.79 | KMO (0.63) | KMOCPA1CPB1CPA3CPB2 | |
| SCHEMBL7312457 | 0.79 | KMO (0.71) | KMOCPA1CPB1CPA3CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |