Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632954 | 0.73 | HPGD (0.41) | ALDH1A1HPGDALOX15HSD17B10RECQL | |
| SCHEMBL2142605 | 0.71 | ALDH1A1 (0.42) | ALDH1A1HPGDALOX15HSD17B10RECQL | |
| SCHEMBL6630598 | 0.71 | PTPN22 (0.41) | ALDH1A1HPGDALOX15HSD17B10RECQL | |
| SCHEMBL5030608 | 0.71 | PTPN22 (0.47) | ALDH1A1HPGDHSD17B10RECQLTDP1 | |
| SCHEMBL7306152 | 0.67 | PIM1 (0.42) | ALDH1A1HPGDALOX15HSD17B10RECQL | |
| SCHEMBL152947 | 0.64 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10THRBTSHR | |
| SCHEMBL6629484 | 0.64 | HSD17B10 (0.37) | ALDH1A1HPGDALOX15HSD17B10RECQL | |
| SCHEMBL2411872 | 0.62 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10TDP1TSHR | |
| SCHEMBL18716074 | 0.61 | HPGD (0.62) | ALDH1A1HPGDALOX15HSD17B10RECQL | |
| SCHEMBL6349397 | 0.61 | CDK2 (0.69) | ALDH1A1HPGDALOX15HSD17B10RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| CN-1091432-A | Can suppress the active peptide of hiv protease, its preparation with and medical use | SANKYO CO (JP) | 1994-08-31 | — | — | CN | disclosed |
| CN-1091128-A | Piperidine derivative | SANKYO CO (JP) | 1994-08-24 | — | — | CN | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0583971-A1 | Piperidine derivatives | SANKYO COMPANY LIMITED (JP) | 1994-02-23 | — | — | EP | disclosed |
| CN-1064683-A | New beta-amino-alpha-hydroxycarboxylic acids and uses thereof | SANKYO CO (JP) | 1992-09-23 | — | — | CN | disclosed |
| EP-0498680-A1 | New beta-amino-alpha-hydroxycarboxylic acids and their use | Sankyo Company Limited (JP) | 1992-08-12 | — | — | EP | disclosed |