Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555003 | 0.84 | IDO1 (0.78) | IDO1EPHX1EPHX2MAPTGAA | |
| SCHEMBL29838484 | 0.81 | GAA (0.67) | IDO1EPHX1EPHX2MAPTGAA | |
| SCHEMBL21807612 | 0.81 | IDO1 (0.61) | IDO1EPHX1EPHX2MAPTGAA | |
| SCHEMBL526255 | 0.81 | GAA (0.67) | IDO1EPHX1EPHX2MAPTGAA | |
| SCHEMBL8296719 | 0.81 | IDO1 (0.61) | IDO1EPHX1EPHX2MAPTGAA | |
| SCHEMBL5450586 | 0.80 | ALDH1A1 (0.71) | IDO1MAPTGAALMNAALDH1A1 | |
| SCHEMBL1092135 | 0.78 | EPHX1 (0.73) | IDO1EPHX1EPHX2MAPTGAA | |
| SCHEMBL10660750 | 0.78 | IDO1 (0.68) | IDO1EPHX1EPHX2MAPTGAA | |
| SCHEMBL4555049 | 0.78 | MEN1 (0.68) | IDO1EPHX1EPHX2MAPTGAA | |
| SCHEMBL5988806 | 0.78 | IDO1 (1.00) | IDO1EPHX1EPHX2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674864-A | ANALGESICS; ENDOPEPTIDASE AND ENKEPHALINASE INHIBITORS; CARDIOTONIC, PSYCHOTROPIC AND HYPERTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1997-10-07 | — | — | US | disclosed |
| EP-0465369-B1 | N-substituted derivatives of alpha-mercapto alkylamines, process for their preparation and intermediates obtained, their use as medicaments and compositions containing them | ROUSSEL UCLAF (FR) | 1994-04-13 | — | — | EP | disclosed |
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |