Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 7/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409974 | 1.00 | PLA2G7 (0.50) | PLA2G7MAPTELANEALDH1A1TSHR | |
| SCHEMBL8627827 | 1.00 | PLA2G7 (0.50) | PLA2G7MAPTELANEALDH1A1TSHR | |
| SCHEMBL209658 | 1.00 | PLA2G7 (0.50) | PLA2G7MAPTELANEALDH1A1TSHR | |
| SCHEMBL209659 | 1.00 | PLA2G7 (0.50) | PLA2G7MAPTELANEALDH1A1TSHR | |
| SCHEMBL8547007 | 0.93 | PLA2G7 (0.45) | PLA2G7MAPTELANEALDH1A1TSHR | |
| SCHEMBL7045591 | 0.87 | ELANE (0.41) | PLA2G7MAPTELANEALDH1A1TSHR | |
| SCHEMBL25377184 | 0.86 | PLA2G7 (0.58) | PLA2G7MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL2635874 | 0.86 | PLA2G7 (0.58) | PLA2G7MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL2635878 | 0.86 | PLA2G7 (0.58) | PLA2G7MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL11330082 | 0.86 | ELANE (0.41) | PLA2G7MAPTELANETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2014 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118020766-A | High-dispersion wettability auxiliary agent and application thereof | 河北成悦化工有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-114805711-B | Preparation method of polymer-based acid-base catalyst with isolated space sites | 浙江理工大学 | 2024-01-30 | — | — | CN | claimed |
| CN-110498823-B | Synthetic method of 6' -N-ethyl gentamicin C1a | 无锡济煜山禾药业股份有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-111040007-B | Synthetic method of 1, 3, 2' -N, N, N-triacetyl gentamicin C1a | 无锡济煜山禾药业股份有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-114805711-A | Preparation method of polymer-based acid-base catalyst with isolated spatial sites | 浙江理工大学 | 2022-07-29 | — | — | CN | claimed |
| CN-111039999-A | Synthesis method of etimicin impurity | 无锡济民可信山禾药业股份有限公司 | 2020-04-21 | — | — | CN | claimed |
| CN-111040007-A | Synthetic method of 1, 3, 2' -N, N, N-triacetyl gentamicin C1a | 无锡济民可信山禾药业股份有限公司 | 2020-04-21 | — | — | CN | claimed |
| CN-110498823-A | A kind of synthetic method of 6 \"-N- ethyl Gentamicin C1as | WUXI JIMIN KEXIN SHANHE PHARM | 2019-11-26 | — | — | CN | claimed |
| CN-102827067-B | Beta-lactamase inhibitor | SCHERING CORPORATION (US) | 2015-09-23 | — | — | CN | claimed |
| US-20130274475-A1 | BETA-LACTAMASE INHIBITORS | MERCK SHARP & DOHME (US) | 2013-10-17 | — | — | US | claimed |
| US-20120053350-A1 | PREPARATION OF ALKYL ESTERS OF N-PROTECTED OXO-AZACYCLOALKYLCARBOXYLIC ACIDS | MERCK SHARP & DOHME CORP. | 2012-03-01 | — | — | US | claimed |
| CN-101918407-A | Beta-lactamase inhibitors | MERCK & CO INC | 2010-12-15 | — | — | CN | claimed |
| WO-2010126820-A2 | PREPARATION OF ALKYL ESTERS OF N-PROTECTED OXO-AZACYCLOALKYLCARBOXYLIC ACIDS | MERCK SHARP & DOHME CORP. (US) | 2010-11-04 | — | — | WO | claimed |
| US-7635573-B2 | Mass spectroscopic method for comparing protein levels in two or more samples | AGILENT TECHNOLOGIES, INC. (US) | 2009-12-22 | — | — | US | claimed |
| US-7432391-B2 | Process for the production of tert-butyl N-(2-bromoethyl)carbamate | DAITO CHEMIX CORPORATION (JP) | 2008-10-07 | — | — | US | claimed |
| US-20080139839-A1 | Process For the Production of Tert-Butyl N-(2-Bromoethyl)Carbamate | DAITO CHEMIX CORPORATION (JP) | 2008-06-12 | — | — | US | claimed |
| CN-1858052-A | Quinolone carboxylate compounds and their preparing method and use | SHANGHAI INST OF MEDICINE CAS (CN) | 2006-11-08 | — | — | CN | claimed |
| US-20060134723-A1 | N-or C-terminal peptide selection method for proteomics | FISCHER STEVEN M | 2006-06-22 | — | — | US | claimed |
| WO-1999058152-A1 | CATIONIC LIPIDS WITH DISULPHIDE BONDS FOR THE INTRACELLULAR DELIVERY OF THERAPEUTIC SUBSTANCES | UNIVERSITY OF FLORIDA (US) | 1999-11-18 | — | — | WO | claimed |
| WO-1991004968-A1 | CHALCOGEN-BASED CHIRAL REAGENTS AND METHOD FOR NUCLEAR MAGNETIC RESONANCE DETECTION OF STEREOCHEMICAL ASSIGNMENTS AND ENANTIOMERIC RATIOS AND METHOD FOR SYNTHESIZING SAID REAGENTS | UNIVERSITY OF SOUTH CAROLINA (US) | 1991-04-18 | — | — | WO | claimed |