SCHEMBL209659

SCHEMBL209659

CC(C)(C)OC(=O)ON=C(C#N)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 1/20 0.50
MAPT P10636 2/20 0.44
ELANE P08246 1/20 0.40
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TNF P01375 1/20 0.37
KLF5 Q13887 1/20 0.37
NOD1 Q9Y239 1/20 0.37
USP2 O75604 1/20 0.37
CTSS P25774 7/20 0.36
CTSK P43235 4/20 0.36
AAK1 Q2M2I8 1/20 0.36
LMNA P02545 1/20 0.35
XBP1 P17861 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CTSL P07711 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL409974 1.00 PLA2G7 (0.50) PLA2G7MAPTELANEALDH1A1TSHR
SCHEMBL8627827 1.00 PLA2G7 (0.50) PLA2G7MAPTELANEALDH1A1TSHR
SCHEMBL209658 1.00 PLA2G7 (0.50) PLA2G7MAPTELANEALDH1A1TSHR
SCHEMBL73083 1.00 PLA2G7 (0.50) PLA2G7MAPTELANEALDH1A1TSHR
SCHEMBL8547007 0.93 PLA2G7 (0.45) PLA2G7MAPTELANEALDH1A1TSHR
SCHEMBL7045591 0.87 ELANE (0.41) PLA2G7MAPTELANEALDH1A1TSHR
SCHEMBL25377184 0.86 PLA2G7 (0.58) PLA2G7MAPTALDH1A1TSHRHSD17B10
SCHEMBL2635874 0.86 PLA2G7 (0.58) PLA2G7MAPTALDH1A1TSHRHSD17B10
SCHEMBL2635878 0.86 PLA2G7 (0.58) PLA2G7MAPTALDH1A1TSHRHSD17B10
SCHEMBL11330082 0.86 ELANE (0.41) PLA2G7MAPTELANETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637702-B2 Process for preparing substituted imidazo[1,5-α]pyrazines HOFFMANN-LA ROCHE INC. (US) 2026-05-26 US claimed
CN-122059936-A DASA compound and preparation method and application thereof 中山大学 2026-05-19 CN claimed
WO-2025027521-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF AVIBACTAM AND INTERMEDIATE THEREOF FRESENIUS KABI ONCOLOGY LTD. (IN) 2025-02-06 WO claimed
US-20240391878-A1 METHOD FOR PREPARING TERT-BUTYL (S)-4-(1-(2,3-DIMETHYLPHENYL)ETHYL)-1H-IMIDAZOLE-1-CARBOXYLATE AND SALTS THEREOF AND ITS USE IN A METHOD FOR PREPARING (S)-4-(1-(2,3-DIMETHYLPHENYL)ETHYL)-1H-IMIDAZOLE AND SALTS THEREOF MOEHS IBERICA, S.L. (ES) 2024-11-28 US claimed
EP-4467534-A1 METHOD FOR PREPARING TERT-BUTYL (S)-4-(1-(2,3-DIMETHYLPHENYL)ETHYL)-1H-IMIDAZOLE-1-CARBOXYLATE AND SALTS THEREOF AND ITS USE IN A METHOD FOR PREPARING (S)-4-(1-(2,3-DIMETHYLPHENYL)ETHYL)-1H-IMIDAZOLE AND SALTS THEREOF Moehs Ibérica, S.L. (ES) 2024-11-27 EP claimed
CN-118020766-A High-dispersion wettability auxiliary agent and application thereof 河北成悦化工有限公司 2024-05-14 CN claimed
US-20240150390-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-05-09 US claimed
EP-4286393-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE Daiichi Sankyo Company, Limited (JP) 2023-12-06 EP claimed
CN-116867795-A Novel method for producing antibody-immunostimulant conjugate 第一三共株式会社 2023-10-10 CN claimed
WO-2022163846-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE 第一三共株式会社 2022-08-04 WO claimed
US-20040006137-A1 Asymmetric synthesis of amino-pyrrolidinones and a crystalline, free-base amino-pyrrolidinone BRISTOL-MYERS SQUIBB COMPANY 2004-01-08 US claimed
US-20030139470-A1 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants HAARMANN & REIMER GMBH (DE) 2003-07-24 US claimed
EP-1218338-A1 PREPARATION OF AMINO-PROTECTED LYSINE DERIVATIVES ABBOTT LABORATORIES (US) 2002-07-03 EP claimed
US-20020042536-A1 PREPARATION OF AMINO-PROTECTED LYSINE DERIVATIVES ABBOTT LABORATORIES 2002-04-11 US claimed
US-6313292-B1 REACTION FROM 5-AMINO-2-FLUOROPYRIDINE; AMINATION, CYCLIZATION, CHLORINATION, SALT FORMATION, DECHLORINATION, DEBLOCKING WARNER-LAMBERT COMPANY 2001-11-06 US claimed
WO-2001027074-A1 PREPARATION OF AMINO-PROTECTED LYSINE DERIVATIVES ABBOTT LABORATORIES (US) 2001-04-19 WO claimed
EP-0629189-B1 PREPARATION OF INTERMEDIATES IN THE SYNTHESIS OF QUINOLINE ANTIBIOTICS PFIZER (US) 1997-08-06 EP claimed
EP-0133795-B1 GABA ESTERS AND GABA ANALOGUE ESTERS THE McLEAN HOSPITAL CORPORATION (US) 1989-01-18 EP claimed
WO-1985000520-A1 GABA ESTERS AND GABA ANALOGUE ESTERS THE MCLEAN HOSPITAL CORPORATION (US) 1985-02-14 WO claimed
US-4205183-A Facile method for isolating resolved amino acids BECKMAN INSTRUMENTS, INC. (US) 1980-05-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391878-A1 METHOD FOR PREPARING TERT-BUTYL (S)-4-(1-(2,3-DIMETHYLPHENYL)ETHYL)-1H-IMIDAZOLE-1-CARBOXYLATE AND SALTS THEREOF AND ITS USE IN A METHOD FOR PREPARING (S)-4-(1-(2,3-DIMETHYLPHENYL)ETHYL)-1H-IMIDAZOLE AND SALTS THEREOF ADRA1A, AVPR1A, THRA PLA2G7 4104/4885MAPT 2541/4885ELANE 1146/4885
US-20240150390-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE PAICS, COASY, CDS2 PLA2G7 927/4885MAPT 4562/4885ELANE 4683/4885
US-20040006137-A1 Asymmetric synthesis of amino-pyrrolidinones and a crystalline, free-base amino-pyrrolidinone MMP8, MMP9, ADAM8 PLA2G7 1608/4885MAPT 2460/4885ELANE 131/4885
US-20020042536-A1 PREPARATION OF AMINO-PROTECTED LYSINE DERIVATIVES DNPEP, PHYKPL, KARS1 PLA2G7 2020/4885MAPT 2154/4885ELANE 2179/4885
US-20030139470-A1 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants TYR, HAAO, TH PLA2G7 3428/4885MAPT 1335/4885ELANE 3380/4885
US-12637702-B2 Process for preparing substituted imidazo[1,5-α]pyrazines BCKDK, P4HB, DOHH PLA2G7 2148/4885MAPT 4554/4885ELANE 2147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.