Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.56 |
| ▸ | MAOA | P21397 | 5/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30198995 | 0.78 | MAOB (0.42) | MAOBMAOAFFAR1FFAR4GRM5 | |
| SCHEMBL29097866 | 0.78 | MAOB (0.42) | MAOBMAOAFFAR1FFAR4GRM5 | |
| SCHEMBL30748420 | 0.78 | PNMT (0.51) | — | |
| SCHEMBL2728148 | 0.78 | PNMT (0.51) | — | |
| SCHEMBL11449734 | 0.75 | HRH3 (0.59) | MAOBMAOARXRBRAB9AHRH3 | |
| SCHEMBL29741480 | 0.73 | MAOB (0.81) | MAOBMAOARAB9AHRH3SMPD1 | |
| SCHEMBL18664184 | 0.73 | MAOB (0.81) | MAOBMAOARAB9AHRH3SMPD1 | |
| SCHEMBL2086321 | 0.72 | DRD2 (0.51) | — | |
| SCHEMBL30018898 | 0.72 | DRD2 (0.51) | — | |
| SCHEMBL29098052 | 0.71 | DRD2 (0.60) | MAOBMAOARAB9AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |