Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 6/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316562 | 0.80 | CA12 (0.39) | ALDH1A1LMNATSHRCA12CA14 | |
| SCHEMBL28593227 | 0.72 | TSHR (0.50) | ALDH1A1LMNATSHRRECQLCA12 | |
| SCHEMBL22340222 | 0.67 | TSHR (0.41) | ALDH1A1LMNATSHRRECQLCA12 | |
| SCHEMBL444990 | 0.67 | TSHR (0.58) | ALDH1A1LMNATSHRRECQLCA12 | |
| SCHEMBL18155288 | 0.66 | TSHR (0.52) | ALDH1A1LMNATSHRRECQLCA12 | |
| SCHEMBL12920507 | 0.66 | TSHR (0.52) | ALDH1A1LMNATSHRRECQLCA12 | |
| SCHEMBL14890746 | 0.66 | TSHR (0.47) | ALDH1A1LMNATSHRRECQLL3MBTL1 | |
| SCHEMBL20691171 | 0.66 | POLB (0.44) | ALDH1A1LMNATSHRCA12CA14 | |
| SCHEMBL5979524 | 0.66 | TSHR (0.56) | ALDH1A1LMNATSHRRECQLL3MBTL1 | |
| SCHEMBL5978990 | 0.66 | TSHR (0.56) | ALDH1A1LMNATSHRRECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |