Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 3/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308417 | 0.80 | ALDH1A1 (0.41) | CA12CA9CA7CA14LMNA | |
| SCHEMBL7314215 | 0.73 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2GAATSHR | |
| SCHEMBL31578751 | 0.71 | ALDH1A1 (0.39) | LMNAALDH1A1MAPTMMP1 | |
| SCHEMBL7313272 | 0.69 | LMNA (0.42) | CA12CA9CA7CA14LMNA | |
| SCHEMBL12340194 | 0.69 | LMNA (0.43) | CA12CA9CA7CA14LMNA | |
| SCHEMBL7120092 | 0.69 | EBP (0.47) | CA12CA9CA7CA14LMNA | |
| SCHEMBL7310949 | 0.68 | L3MBTL1 (0.37) | LMNAALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL20545500 | 0.67 | HDAC1 (0.66) | CA12CA9CA7CA14LMNA | |
| SCHEMBL6823634 | 0.67 | HDAC1 (0.56) | CA12CA9CA7CA14LMNA | |
| SCHEMBL12751052 | 0.66 | LMNA (0.47) | CA12CA9CA7CA14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |