Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ITGAM | P11215 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9217427 | 0.95 | ITGB3 (0.49) | ITGB3ITGA2BFOLH1F2TMPRSS6 | |
| SCHEMBL7306316 | 0.94 | ITGB3 (0.51) | ITGB3ITGA2BFOLH1 | |
| SCHEMBL7305759 | 0.89 | ITGB3 (0.54) | ITGB3ITGA2BFOLH1 | |
| Trifluoroacetic Acid SCHEMBL3040708 | 0.85 | ITGB3 (0.50) | ITGB3ITGA2BF2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL9222086 | 0.83 | NPY4R (0.48) | ITGB3ITGA2BF2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL7329305 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2BF2 | |
| SCHEMBL7332658 | 0.82 | ITGB3 (0.52) | ITGB3ITGA2BFOLH1 | |
| Trifluoroacetic Acid SCHEMBL7327825 | 0.82 | ITGB3 (0.42) | ITGB3ITGA2BF2 | |
| SCHEMBL7332549 | 0.81 | FOLH1 (0.49) | ITGB3ITGA2BFOLH1 | |
| Trifluoroacetic Acid SCHEMBL7327815 | 0.80 | ITGB3 (0.43) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | claimed |
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |