Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPRA | P18433 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.47 |
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299599 | 0.95 | ITGB3 (0.51) | ITGB3ITGA2BPTPN1PTPN2PTPRA | |
| SCHEMBL9742835 | 0.95 | ITGB3 (0.51) | ITGB3ITGA2BPTPN1PTPN2PTPRA | |
| Trifluoroacetic Acid SCHEMBL9222086 | 0.93 | NPY4R (0.48) | ITGB3ITGA2BPTPN1PTPN2PTPRA | |
| SCHEMBL7303040 | 0.89 | ITGB3 (0.55) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL13744704 | 0.88 | ITGB3 (0.48) | ITGB3ITGA2BPTPN1PRSS1TMPRSS15 | |
| SCHEMBL7306757 | 0.88 | PRSS1 (0.50) | ITGB3ITGA2BPTPN1PTPN2PTPRA | |
| SCHEMBL7298590 | 0.88 | PRSS1 (0.47) | ITGB3ITGA2BPTPN1PTPN2PTPRA | |
| SCHEMBL13716655 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BPTPN1PTPN2PTPRA | |
| SCHEMBL7304862 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BPTPN1PTPN2PTPRA | |
| SCHEMBL13716830 | 0.86 | L3MBTL1 (0.56) | ITGB3ITGA2BPTPN1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | claimed |
| US-20100041587-A1 | COMBINATION THERAPY FOR INHIBITION OF PLATELET AGGREGATION | PORTER R STEPHEN | 2010-02-18 | — | — | US | disclosed |
| US-20070082840-A1 | Combination therapy for inhibition of platelet aggregation | VDDI PHARMACEUTICALS | 2007-04-12 | — | — | US | disclosed |