Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309049 | 0.94 | LMNA (0.47) | AGTR1AGTR2PPARGKDM4EALDH1A1 | |
| SCHEMBL7310642 | 0.94 | LMNA (0.46) | AGTR1AGTR2PPARGKDM4EALDH1A1 | |
| SCHEMBL7307822 | 0.93 | AGTR1 (0.46) | AGTR1AGTR2PPARGKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8847652 | 0.92 | AGTR1 (0.54) | AGTR1AGTR2PPARGKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL9041862 | 0.90 | AGTR1 (0.44) | AGTR1AGTR2PPARG | |
| SCHEMBL7309295 | 0.90 | AGTR1 (0.42) | AGTR1AGTR2PPARGKDM4EALDH1A1 | |
| SCHEMBL7302801 | 0.88 | LMNA (0.43) | AGTR1AGTR2PPARGKDM4EALDH1A1 | |
| SCHEMBL7306067 | 0.87 | LMNA (0.42) | AGTR1AGTR2PPARGKDM4EALDH1A1 | |
| SCHEMBL8847656 | 0.87 | AGTR1 (0.47) | AGTR1AGTR2PPARGKDM4EALDH1A1 | |
| SCHEMBL7311710 | 0.87 | AGTR1 (0.42) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502314-A1 | Benzimidazol, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-09 | — | — | EP | disclosed |