Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307833 | 0.83 | EBP (0.45) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7309070 | 0.83 | EBP (0.39) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7308385 | 0.83 | EBP (0.39) | EBPSIGMAR1CACNA1B | |
| SCHEMBL8083545 | 0.83 | EBP (0.39) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7306036 | 0.80 | EBP (0.41) | EBPSIGMAR1CACNA1B | |
| SCHEMBL8082767 | 0.79 | CHRM3 (0.38) | EBPSIGMAR1 | |
| SCHEMBL7301361 | 0.79 | EBP (0.45) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7305480 | 0.79 | EBP (0.44) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7306630 | 0.78 | EBP (0.39) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7316565 | 0.78 | EBP (0.37) | EBPSIGMAR1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |