Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7306474 | 0.99 | NPC1 (0.47) | NPC1RAB9ARECQLPOLBKCNH2 | |
| SCHEMBL7319534 | 0.96 | NPC1 (0.47) | NPC1RAB9ARECQLPOLBKCNH2 | |
| SCHEMBL7304281 | 0.95 | NPC1 (0.46) | NPC1RAB9ARECQLPOLBKCNH2 | |
| Hydrochloric Acid SCHEMBL7318295 | 0.95 | NPC1 (0.46) | NPC1RAB9ARECQLPOLBKCNH2 | |
| Hydrochloric Acid SCHEMBL7312489 | 0.94 | NPC1 (0.44) | NPC1RAB9ARECQLPOLBKCNH2 | |
| SCHEMBL7306466 | 0.88 | RAB9A (0.47) | NPC1RAB9ARECQLPOLBKCNH2 | |
| SCHEMBL7318286 | 0.85 | RAB9A (0.46) | NPC1RAB9ARECQLPOLBKCNH2 | |
| SCHEMBL7309641 | 0.84 | L3MBTL1 (0.50) | NPC1RAB9ARECQLKDM4EALDH1A1 | |
| SCHEMBL7312485 | 0.84 | NPC1 (0.44) | NPC1RAB9ARECQLPOLBKCNH2 | |
| SCHEMBL8164415 | 0.83 | NPC1 (0.70) | NPC1RAB9ARECQLPOLBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |