Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30590336 | 0.77 | TNKS2 (0.48) | TNKS2PARP15PARP10PARP2ERCC1 | |
| SCHEMBL31139871 | 0.74 | TNKS2 (0.43) | TNKS2PARP15PARP10PARP2ERCC1 | |
| Trifluoroacetic Acid SCHEMBL29656976 | 0.70 | TNKS2 (0.41) | TNKS2PARP15PARP10PARP2ERCC1 | |
| SCHEMBL7302300 | 0.69 | PDPK1 (0.62) | ALDH1A1KDM4EMEN1KMT2APARP1 | |
| SCHEMBL31549277 | 0.68 | TNKS2 (0.44) | TNKS2PARP15PARP10PARP2ERCC1 | |
| SCHEMBL16776795 | 0.67 | L3MBTL1 (0.43) | TNKS2PARP15ALDH1A1KDM4ETNKS | |
| SCHEMBL1549859 | 0.67 | TNKS2 (0.60) | TNKS2PARP15PARP10PARP2ERCC1 | |
| SCHEMBL2539403 | 0.67 | KDM4E (0.58) | TNKS2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL993597 | 0.65 | KMT2A (0.66) | TNKS2PARP15PARP10PARP2ERCC1 | |
| SCHEMBL3359790 | 0.65 | DAO (0.53) | TNKS2PARP15PARP10PARP2TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505058-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1997-05-21 | — | — | EP | disclosed |
| EP-0503844-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-5219864-A | Prevention, treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| US-5155115-A | THIENOPYRIDINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0505058-A1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |
| EP-0503844-A1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |