Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297662 | 0.78 | PDPK1 (0.65) | PDPK1KDM4EALDH1A1DAOTSHR | |
| SCHEMBL22144475 | 0.77 | PDPK1 (0.62) | PDPK1ALDH1A1DAOTSHRHTT | |
| SCHEMBL5462003 | 0.77 | PDPK1 (0.57) | PDPK1KDM4EALDH1A1DAOHPGD | |
| SCHEMBL29859817 | 0.70 | PDPK1 (0.46) | PDPK1TSHR | |
| SCHEMBL29859622 | 0.69 | PDPK1 (0.53) | PDPK1DAOTSHRHTTSMN1; SMN2 | |
| SCHEMBL7308544 | 0.69 | TNKS2 (0.51) | PDPK1KDM4EALDH1A1KDM5ADAO | |
| Hydrochloric Acid SCHEMBL29859578 | 0.68 | PDPK1 (0.51) | PDPK1DAOTSHRHTTSMN1; SMN2 | |
| SCHEMBL29859617 | 0.68 | PDPK1 (0.47) | PDPK1TSHRHPGD | |
| SCHEMBL6923624 | 0.67 | GRIN2D (0.56) | PDPK1DAOTSHRMAPTKMT2A | |
| SCHEMBL21048284 | 0.67 | PDPK1 (0.50) | PDPK1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227100-B | Thienopyridone compounds | 詹森药业有限公司 | 2023-05-05 | — | — | CN | disclosed |
| US-20220213123-A1 | THIENOPYRIDINONE COMPOUNDS | JOHNSON & JOHNSON (CHINA) INVESTMENT LTD. (CN) | 2022-07-07 | — | — | US | disclosed |
| CN-113227100-A | Thienopyridone compounds | 詹森药业有限公司 | 2021-08-06 | — | — | CN | disclosed |
| WO-2020135483-A1 | THIENOPYRIDINONE COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2020-07-02 | — | — | WO | disclosed |
| EP-0505058-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1997-05-21 | — | — | EP | disclosed |
| EP-0503844-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-5219864-A | Prevention, treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| US-5155115-A | THIENOPYRIDINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0505058-A1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |
| EP-0503844-A1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213123-A1 | THIENOPYRIDINONE COMPOUNDS | FGFR3, FGFR1, FGFR2 | PDPK1 143/4885KDM4E 573/4885ALDH1A1 1260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.