Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21830431 | 0.82 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2MAPK1MAOA | |
| SCHEMBL17912823 | 0.82 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2MAPK1MAOA | |
| SCHEMBL8125448 | 0.81 | MGAM (0.43) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL1402324 | 0.79 | IDO1 (0.47) | KDM4EALDH1A1MAPK1MAOAMAPT | |
| SCHEMBL16641096 | 0.79 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2MAPK1MAOA | |
| SCHEMBL1193759 | 0.78 | CYP1A2 (0.52) | KDM4EALDH1A1SMN1; SMN2MAPK1MAOA | |
| SCHEMBL21830568 | 0.78 | CYP19A1 (0.46) | KDM4EALDH1A1SMN1; SMN2MAPK1MAOA | |
| SCHEMBL1047908 | 0.77 | SMN1; SMN2 (0.50) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL911283 | 0.77 | MAPT (0.50) | KDM4EALDH1A1SMN1; SMN2MAPK1MAOA | |
| SCHEMBL5254065 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2MAPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |