Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463006 | 1.00 | MAPT (0.50) | MAPTALDH1A1TP53KDM4EMAPK1 | |
| SCHEMBL19612240 | 0.82 | MAPT (0.63) | MAPTALDH1A1TP53KDM4EMAPK1 | |
| SCHEMBL17912823 | 0.82 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4EMAPK1LMNA | |
| SCHEMBL3171781 | 0.79 | MAPT (0.64) | MAPTALDH1A1TP53KDM4EMAPK1 | |
| SCHEMBL30312309 | 0.79 | MAPT (0.64) | MAPTALDH1A1TP53KDM4EMAPK1 | |
| SCHEMBL12804048 | 0.79 | MAPT (0.48) | MAPTALDH1A1TP53KDM4EMAPK1 | |
| SCHEMBL16641096 | 0.79 | ALDH1A1 (0.50) | MAPTALDH1A1TP53KDM4EMAPK1 | |
| SCHEMBL9628286 | 0.78 | EP300 (0.65) | MAPTALDH1A1TP53KDM4EMAPK1 | |
| SCHEMBL1193759 | 0.78 | CYP1A2 (0.52) | MAPTALDH1A1KDM4EMAPK1CYP3A4 | |
| SCHEMBL186826 | 0.77 | MAPT (0.67) | MAPTALDH1A1TP53KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116381105-A | Shennong hundred flower honey characteristic marker and screening method and application thereof | 华中农业大学 | 2023-07-04 | — | — | CN | claimed |
| CN-102993157-B | Alpha-naphthoflavone derivative, preparation method and application thereof | UNIV SHANGHAI JIAOTONG | 2015-04-01 | — | — | CN | claimed |
| CN-102993157-A | Alpha-naphthoflavone derivative, preparation method and application thereof | UNIV SHANGHAI JIAOTONG | 2013-03-27 | — | — | CN | claimed |
| CN-116381105-A | Shennong hundred flower honey characteristic marker and screening method and application thereof | 华中农业大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-102993157-B | Alpha-naphthoflavone derivative, preparation method and application thereof | UNIV SHANGHAI JIAOTONG | 2015-04-01 | — | — | CN | disclosed |
| CN-102993157-A | Alpha-naphthoflavone derivative, preparation method and application thereof | UNIV SHANGHAI JIAOTONG | 2013-03-27 | — | — | CN | disclosed |
| US-7868017-B2 | 9-azabicyclo[3.3.1]nonane derivatives | N.V. ORGANON (NL) | 2011-01-11 | — | — | US | disclosed |
| EP-1934212-A1 | 9-AZABICYCLO [3 . 3 . 1]NONANE DERIVATIVES AS MONOAMINE REUPTAKE INHIBITORS | N.V. Organon (NL) | 2008-06-25 | — | — | EP | disclosed |
| US-20070112019-A1 | 9-Azabicyclo[3.3.1]nonane derivatives | N.V. ORGANON (NL) | 2007-05-17 | — | — | US | disclosed |
| WO-2007039563-A1 | 9-AZABICYCLO [3 . 3 . 1] NONANE DERIVATIVES AS MONOAMINE REUPTAKE INHIBITORS | N.V. ORGANON (NL) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112019-A1 | 9-Azabicyclo[3.3.1]nonane derivatives | AZI2, TPMT, TET3 | MAPT 2936/4885ALDH1A1 441/4885TP53 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.