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SCHEMBL7308562

SCHEMBL7308562

CCCc1nc(C(=O)O)c(C(=O)O)n1Cc1ccc(-c2ccccc2C2(C(c3ccccc3)(c3ccccc3)c3ccccc3)N=NN=N2)cc1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ AGTR1 P30556 2/20 0.47
▸ AGTR2 P50052 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7310582 0.95 AGTR2 (0.49) AGTR1AGTR2
SCHEMBL7304485 0.91 AGTR1 (0.53) AGTR1
SCHEMBL8845238 0.90 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL1970345 0.89 AGTR1 (0.61) AGTR1AGTR2
SCHEMBL7312391 0.89 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL7310118 0.88 AGTR1 (0.54) AGTR1AGTR2
Water SCHEMBL2576561 0.88 AGTR1 (0.60) AGTR1AGTR2
SCHEMBL3342427 0.88 AGTR1 (0.60) AGTR1AGTR2
SCHEMBL7312362 0.86 AGTR1 (0.50) AGTR1AGTR2
SCHEMBL7303319 0.85 AGTR2 (0.47) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0503785-A1 1-Biphenylimidazole derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1992-09-16 — — EP disclosed