SCHEMBL7308624

SCHEMBL7308624

CCc1nc(C2CC2)c(C(=O)O)n1Cc1ccc2oc(-c3ccccc3C(=O)OC(C)(C)C)c(Br)c2c1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9429521 0.93
SCHEMBL7312302 0.91 AGTR1 (0.51) AGTR1
SCHEMBL9429563 0.87 AGTR1 (0.47) AGTR1
SCHEMBL9663216 0.86 AGTR1 (0.50) AGTR1
SCHEMBL8544352 0.84
SCHEMBL7310859 0.84
SCHEMBL9664761 0.84
SCHEMBL9664203 0.83 AGTR1 (0.48) AGTR1
SCHEMBL9664193 0.83 AGTR1 (0.48) AGTR1
SCHEMBL9318410 0.82 AGTR1 (0.44) AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514193-A1 N-linked imidazolyl-methyl benzofuran derivatives with antihypotensive activity GLAXO GROUP LIMITED (GB) 1992-11-19 EP disclosed