Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312302 | 0.92 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL9429521 | 0.92 | — | — | |
| SCHEMBL8545685 | 0.90 | — | — | |
| SCHEMBL9309599 | 0.90 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL9429613 | 0.89 | — | — | |
| SCHEMBL8544352 | 0.88 | — | — | |
| SCHEMBL7308624 | 0.87 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL8548665 | 0.86 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL9309360 | 0.85 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL8544605 | 0.85 | ALOX5 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310927-A | Hypotensive agents; cognition activators; imidazolyl-2-aryl derivatives | GLAXO GROUP LIMITED (GB) | 1994-05-10 | — | — | US | disclosed |